PReS-FINAL-1016: Micro vesicles as a magnifying glass; uncovering potential biomarkers in juvenile idiopathic arthritis

Introduction Juvenile idiopathic arthritis (JIA) is a common chronic inflammatory diseases in childhood. Despite remission as a result of a plethora of treatment techniques, the chronic and relapsing nature of the disease requires continuous treatment which causes adverse side effects. It is important to uncover a biomarker that can efficiently predict patient responses to therapy as well as determine if patients will progress or regress as a result of treatment. Micro vesicles are key messengers containing many immune signaling molecules including cytokines, molecules known to play a major role in JIA.